| Title | Description |
| FDA Approves New Lung Cancer Diagnostic "Cobas EGFR Mutation Test" |
The U.S. Food and Drug Administration (FDA) has approved the cobas EGFR Mutation Test, a companion diagnostic for the cancer drug Tarceva (erlotinib). This is the first FDA-approved companion diagnostic that detects epidermal growth factor receptor (EGFR) gene mutations, which are present in approximately 10 percent of non-small cell lung cancers (NSCLC)... |
| Syndax Pharmaceutical To Commercialize First-in-Class Lung Cancer Treatment Developed At The University Of Colorado |
Licensing agreement allows development of a novel combination therapeutic for non-small-cell lung carcinoma, a type of lung cancer difficult to treat with conventional chemotherapy... |
| Detecting Recurrent Lung Cancer At An Earlier Stage Using Minimal Dose CT |
Lung cancer is associated with very high mortality, in part because it is hard to detect at early stages, but also because it can recur frequently after surgical removal. The question arises as to what is the best way to follow lung cancer patients after surgery in order to spot problems early enough, before symptoms become obvious, so that patients may still be eligible for new interventions... |
| CT Screening Reduces Lung Cancer Deaths |
CT (computed tomography) screening can reduce lung cancer deaths among high-risk individuals, according to results from the National Lung Cancer Study... |
| Diabetes Drug Makes Lung Cancer Vulnerable To Radiotherapy |
THE DIABETES drug metformin slows the growth of lung cancer cells and makes them more likely to be killed by radiotherapy, according to a study published in the British Journal of Cancer this week... |
| Dogs Can Detect Breast And Lung Cancer Cells In Vitro |
Researcher Hopes to Screen Smokers with Early Stage Lung Disease in Next Research Phase An internist and instructor at Ben-Gurion University of the Negev has conducted research proving that specially trained dogs can differentiate the smell of breast cancer cells from non-cancerous cells in cell cultures... |
| Lung Cancer Survival Improved By Chemo, Radiation, Then Surgery |
In one of the largest observational studies of its kind, researchers report that a combination of chemotherapy and radiation followed by surgery in patients with stage 3 non-small cell lung cancer improves survival. Patients who had chemoradiation therapy followed by surgery had twice the five-year survival rate of those who had only chemoradiation, says Dr... |
| Studying The Effect Of Stem Cell Therapy On Cancer |
Injection of human stem cells into mice with tumors slowed down tumor growth, finds research published in BioMed Central's open access journal Stem Cell Research & Therapy. Human mesenchymal stem cells (MSC), isolated from bone marrow, caused changes in blood vessels supplying the tumor, and it is this modification of blood supply which seems to impact tumor growth... |
| Cancer Experts Detail Advanced Radiosurgery Treatments For Lung Cancer Using Varian Medical Systems Technologies |
More than 800 oncology professionals at European Society for Radiotherapy and Oncology forum hear of pioneering treatment delivery, motion management and tumor-tracking technologies for tackling the growing lung cancer burden Cancer experts have reported future trends and progress in radiotherapy treatments for lung cancer using motion management and tumor-tracking technologie... |
| Primary Care Provider Density Affects Lung Cancer Mortality Rates |
Lung cancer remains the leading cause of cancer-related deaths and is tied as the third leading cause of death overall in industrialized countries. Within the United States, several groups identified by race, sex, and socioeconomic status have been linked to increased cancer mortality, suggesting a disparity because of these characteristics... |
| Patients With Lung Cancer Who Carry Specific HER2 Mutations May Benefit From Certain Anti-HER2 Treatments |
New results from a retrospective study conducted in Europe suggest that anti-HER2 treatments, like the widely used breast cancer agent trastuzumab (Herceptin), have anti-cancer effects in a small subset of patients with advanced non-small cell lung cancer (NSCLC) harboring specific HER2 protein mutations... |
| Two Items Key To Decrease Symptoms And Prolong Survival For Leptomeningeal Carcinomatosis Patients |
Lung cancer is one of the most common primary cancers that cause leptomeningeal carcinomatosis (LMC), when cancer spreads to the membranes surrounding the spinal cord and brain. Cases of LMC have increased because of the improved survival of lung cancer patients with the help of new advances in treatment... |
| Dispelling The Myth That Smoking From Hookah Is A Harmless Alternative To Cigarettes |
Smoking tobacco through a hookah is a pastime gaining popularity among the college crowd, but many of them mistakenly believe that using the fragrant water pipe is less harmful than smoking cigarettes. In a new study at UC San Francisco, researchers measuring chemicals in the blood and urine concluded that hookah smoke contains a different - but still harmful - mix of toxins... |
| Doctors Out-Maneuvered By Mathematical Models In Predicting Cancer Patients' Responses To Treatment |
Mathematical prediction models are better than doctors at predicting the outcomes and responses of lung cancer patients to treatment, according to new research presented at the 2nd Forum of the European Society for Radiotherapy and Oncology (ESTRO)... |
| ACE Inhibitor Can Limit Radiation Damage To Lungs And Heart For Cancer Patients |
Unavoidable damage caused to the heart and lungs by radiotherapy treatment of tumours in the chest region can be limited by the administration of an ACE inhibitor, a drug commonly used in the treatment of cardiovascular disease, a group of Dutch researchers have found... |
| 84 Percent Of Lung Cancer Patients Taking Crizotinib Found To Have Low Testosterone |
A previous study by the University of Colorado Cancer Center reported the common side effect of low testosterone in men treated with the recently approved lung cancer agent, crizotinib... |
| Size Of Lesions Seen On Chest CT Images Affected By Radiation Dose Level |
The estimated size of chest lymph nodes and lung nodules seen on CT images varies significantly when the same nodes or nodules are examined using lower versus higher doses of radiation, a new study shows. The size of lymph nodes and lung nodules is an important determinant of treatment and treatment success... |
| Advanced Cancers That Have Spread To The Lungs Can Be Treated Using Cryoablation |
Frozen balls of ice can safely kill cancerous tumors that have spread to the lungs, according to the first prospective multicenter trial of cryoablation. The results were presented at the Society of Interventional Radiology's 38th Annual Scientific Meeting in New Orleans... |
| New Drug Target Discovered For Metastatic Breast Cancer |
Research led by Dr. Suresh Alahari, Professor of Biochemistry and Molecular Biology at LSU Health Sciences Center New Orleans, is the first to report that two specific tumor suppressor genes work in concert to inhibit the growth and spread of breast tumor cells to the lungs. The research is published online in the Journal of Biological Chemistry... |
| Lung Cancer Risk Greatly Increased By Asbestos Exposure, Asbestosis, And Smoking Combined Greatly Increase |
The chances of developing lung cancer associated with asbestos exposure, asbestosis and smoking are dramatically increased when these three risk factors are combined, and quitting smoking significantly reduces the risk of developing lung cancer after long-term asbestos exposure, according to a new study... |
| Reactivation Of Six2 Homeoprotein Allows Breast Cancer Cells To Detach And Metastasize |
In results presented at the AACR Annual Meeting 2013, researchers from the University of Colorado Cancer Center show that the Six2 homeoprotein, while not involved in primary tumor growth, allows cells to detach from substrate and survive their transition through the bloodstream to faraway sites of metastasis. "Here we show for the first time that Six2 causes breast cancer progression... |
| In Bladder Cancer Metastasis, A Little Molecule Makes A Big Difference |
In order to kill, bladder cancer must metastasize, most commonly to the lung - what are the differences between bladder cancers that do and do not make this deadly transition? Research presented by the Director of the University of Colorado Cancer Center at the AACR Annual Meeting 2013 shows that one big difference is a little molecule known as hsa-miR-146a... |
| Nearly 6 Percent Of Lung Cancer Tissue Samples From Non-Smokers Show Signs That HPV May Have Triggered The Tumors |
A common virus known to cause cervical and head and neck cancers may also trigger some cases of lung cancer, according to new research presented by Fox Chase Cancer Center at the AACR Annual Meeting 2013. Examining tissue samples from lung cancer patients, the researchers found that nearly 6% showed signs they may have been driven by a strain of human papillomavirus (HPV) known to cause cancer... |
| Combination Of 2 Existing Drugs Appears Safe In Patients Who Have Not Responded To Previous Treatments For Resistant Lung Cancer |
A new chemotherapy regimen appears to produce minimal side effects in patients with lung cancer that has not responded to previous therapy, paving the way for additional research to determine if the new regimen also helps shrink tumors, according findings to be presented by Fox Chase Cancer Center researchers at the AACR Annual Meeting 2013... |
| Genes Related To The Regulation Of The Cell Cycle Are Associated With Poor Patient Outcomes In Lung And Bladder Cancers |
Believe it or not, while researchers have explored which genes are mutated in each type of tobacco-associated cancer, until now no one had thought to look across these types for common genes that might predict patient outcomes... |
