| Title | Description |
| After Trauma, Transplant Patient Outcomes Better Than Expected |
In the largest study of its kind, physicians from the Department of Surgery at the University of Maryland School of Medicine and the R Adams Cowley Shock Trauma Center at the University of Maryland Medical Center (UMMC) have determined that outcomes for traumatic injury in patients with organ transplants are not worse than for non-transplanted patients, despite common presumpti... |
| A Step Closer To Low-Cost, Implantable Electronics |
New technology under development at The Ohio State University is paving the way for low-cost electronic devices that work in direct contact with living tissue inside the body. The first planned use of the technology is a sensor that will detect the very early stages of organ transplant rejection... |
| Increased Use Of Split Liver Transplants For Young Children Could Significantly Increase Pediatric Organ Donor Pool |
A new study shows that when a liver from a deceased adult or adolescent donor is split into two separate portions for transplantation - with the smaller portion going to a young child and the larger to an adult - the smaller portion used for the child will last just as long as if the child had received a whole organ from a donor close to his size... |
| Significant Mortality Rate Among Adolescent Non-Adhering Heart Transplant Recipients |
After receiving an organ transplant, patients must follow a regimented medication routine to maintain the health of their graft (transplanted organ). Failure to do so, known as non-adherence (NA), can result in life-threatening illness... |
| Groundbreaking Research - MIT Scientists Produce Artificial Liver Tissue |
Groundbreaking research conducted at MIT has found a way of growing liver cells in a lab dish, capable of producing new liver tissue. The liver is capable of regenerating itself if a part of it is removed... |
| Operation Death Rates Higher At The End Of The Week and At Weekend |
A higher death risk for patents who have elective surgery later in the week and on weekends has been found, compared with those earlier in the week, according to new research published in BMJ. Earlier studies have suggested a notably higher risk of death if admitted as an emergency patient during the weekend compared with weekdays... |
| Discovery May Improve Bone Marrow Transplantation |
Blood diseases such as leukemia, multiple myeloma, and myelodysplasia can develop from abnormal bone marrow cells and a dysfunctional bone marrow microenvironment that surrounds these cells. Until now, researchers have been unable to replace the cells that make up the bone marrow microenvironment... |
| Researchers Hope To Recycle Kidneys To Help solve Donor Organ shortage |
Nearly 20 percent of kidneys that are recovered from deceased donors in the U.S. are refused for transplant due to factors ranging from scarring in small blood vessels of the kidney's filtering units to the organ going too long without blood or oxygen... |
| Signals Identified That Direct The Immune System To Reject A Transplanted Organ |
Organ transplant rejection occurs when the transplant recipient's immune system identifies the transplanted organ as foreign tissue and attacks it. It was previously thought that T cells, the immune cells that mediate rejection, must first be activated by molecules known as chemokines in order to migrate to the transplanted organ... |
| Experts Challenge Assumption, Describe Pathway That Leads To Organ Rejection |
Transplant researchers at the University of Pittsburgh School of Medicine challenge a long-held assumption about how biologic pathways trigger immune system rejection of donor organs in a report published online today in the Journal of Clinical Investigation... |
| Robotic Kidney Transplants May Be Best Option For Obese Patients |
Obese patients who received robotic kidney transplants had fewer wound complications than patients who received traditional "open" transplant surgery, according to surgeons at the University of Illinois Hospital & Health Sciences System. The findings should allow more obese patients to receive kidney transplants... |
| Transplant Of Biomaterial Effective In Mice With Type 1 Diabetes |
Researchers have made a significant first step with newly engineered biomaterials for cell transplantation that could help lead to a possible cure for Type 1 diabetes, which affects about 3 million Americans... |
| Disparities In Kidney Transplants For African-Americans |
While the percentage of kidney transplants involving live donors has remained stable for other minority populations, African Americans have seen a decline in live donors even as more of them receive kidney transplants, according to a study by Henry Ford Hospital in Detroit. Those findings were presented at the annual meeting of the American Urological Association in San Diego... |
| Successful Corneal Transplant With Pre-Loaded Donor Tissue: A First For Massachusetts Eye And Ear |
The first successful cornea transplant with donor endothelial tissue preloaded by an eye bank has been performed at Massachusetts Eye and Ear in Boston, Mass. Roberto Pineda II, M.D., Director of the Refractive Surgery Service at Mass. Eye and Ear, and an Associate Professor of Ophthalmology at Harvard Medical School, recently performed the groundbreaking transplant. Dr... |
| Pumpless Paracorporeal Assist Device Helps Infants With Severe Respiratory Failure Survive Until Lung Transplantation |
Adults with end-stage respiratory failure and pulmonary hypertension requiring ECMO (extracorporeal membrane oxygenation) have been "bridged" toward lung transplantation with novel lung assist devices such as the Novalung. This and related devices work based on pumpless application of oxygenators. A presentation by David M... |
| News From The Annals Of Internal Medicine: May 7, 2013 |
1. Ambrisentan Not Appropriate for Patients with Idiopathic Pulmonary Fibrosis Ambrisentan should not be used to treat patients for idiopathic pulmonary fibrosis (IPF). IPF is a fatal form of chronic, progressive lung disease characterized by irreversible scarring around both lungs. IPF causes about 5,000 deaths each year and currently there is no approved treatment... |
| Mathematics, Nature, Help Researchers Understand The Immune System And Its Role In Cancer |
Can the patterns in tree branches or the meandering bends in a river provide clues that could lead to better cancer therapies? According to a new study from Virginia Commonwealth University Massey Cancer Center, these self-similar, repeating patterns in nature known as fractals help scientists better understand how the immune system is organized and may one day be used to help ... |
| Two-Year-Old Girl Born Without A Windpipe Receives Artificial Trachea Grown From Stem Cells |
A two-year-old girl who was born without a windpipe had one grown from her own stem cells - making her the youngest person in the world to successfully benefit from this groundbreaking procedure. Hannah Warren was born in August 2010 in Seoul, South Korea without a windpipe. She could not breathe, eat, drink, or swallow on her own. Until she was brought to the U.S... |
| Combined Liver-Kidney Transplantation May Benefit Some Patients With Complicated Childhood Polycystic Kidney Disease |
A collaborative team of physician-scientists at the Medical College of Wisconsin (MCW) and Children's Hospital of Wisconsin Research Institute has developed a new evidence-based, clinical algorithm to help physicians treat complex patients with autosomal recessive polycystic kidney disease (ARPKD). Their invited manuscript, written by Grzegorz Telega, M.D... |
| Are Living Liver Donors At Risk From Life-Threatening "Near-Miss" Events? |
A study published in Liver Transplantation, a journal of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, reports that donor mortality is about 1 in 500 donors with living donor liver transplantation (LDLT)... |
| Half Of Americans Would Consider Donating A Kidney To A Stranger According To Poll |
Good news for anyone needing a transplant; a new Mayo Clinic survey shows that the public's support for both living and deceased organ donation is increasing... |
| Lab-Grown Kidney Transplanted Into Rats Produces Urine |
US scientists have grown kidneys that produce rudimentary urine in the lab and also after being transplanted into rats. They hope to refine the approach so one day it is possible to grow human kidneys in the lab that work as well as donor kidneys in transplant patients but without the need for them to take drugs to suppress their immune system... |
| Tool Created To Help Patients Decide Whether To Take A Kidney Transplant Immediately Or Wait For A Better One |
Johns Hopkins scientists have created a free, Web-based tool to help patients decide whether it's best to accept an immediately available, but less-than-ideal deceased donor kidney for transplant, or wait for a healthier one in the future... |
| High Survival Rate In Liver Transplantation For Patients With Genetic Liver Conditions |
Journal of American College of Surgeons study reports that, despite the risks and the costs, liver transplant may also serve as a model for gene therapy through solid organ transplantation for some patients... |
| Liver Transplant Eligibility May Be Affected By Incarceration, Marijuana Use And Suicide Attempts |
Results from an anonymous survey of U.S. transplant providers report that incarceration, marijuana use, and psychiatric diagnoses, particularly suicide attempts, may lower patients' eligibility for liver transplantation... |
